May 12, 2007

Researching Parkinson's


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The last three decades of research have gone a long way to lay foundations for a range of modern tests, trials and research into the causes and cures of Parkinson's. It is hoped...


The last three decades of research have gone a long way to lay foundations for a range of modern tests, trials and research into the causes and cures of Parkinson's. It is hoped that further progression in terms of research will ensure that in the near future, patients can benefit from heightened levels of more effective treatment and perhaps even the elusive cure, or prevention methods. Whilst some researchers are investigating the condition, and how it impacts upon the body and the brain, others focus primarily on the four main causal theories, and are attempting to definitively come up with solutions to these causes. Of the millions spent each year in research, results are slow, although comfort can be taken in the fact that they are progressing all the time, and there is a reasonable chance we will know more tomorrow than we did today about this dreadful condition.

Another subject under scrutiny is the possibility of surgically grafting nerves to the brain to promote the production of the drug dopamine, vital for movement. Until now, no procedure or treatment has come close to achieving this goal, and this is something that is the subject of numerous trials and tests to figure the most effective method of surgery as well as the actual probability of success of such an operation.

Additionally, the discovery of toxins which induce the condition has allowed scientists to continue testing to learn more about the mechanisms of Parkinson's, and how the disease evolves and develops within patients. It is now possible to artificially induce the condition in animals under laboratory conditions, and come up with suitable ways of calming the symptoms, or perhaps preventing them altogether.

Other subjects under investigation relate to the drugs currently available for treatment of Parkinson's disease and the development thereof, with particular emphasis on controlled-release properties, which would act to minimise the potential side effects and maximise the impact of the drugs designed to promote dopamine within the brain. Another treatment in testing involves the implant of dopamine capsules into the brain, with timed release capabilities, although these are still some way off mainstream medical consideration.

Scientists are also concerned with different ways in which dopamine can be created in other parts of the brain. In animal testing, it has been shown that by increasing dopamine production elsewhere in the brain, the symptoms of Parkinson's can be somewhat alleviated, which is thought to have transferable potential for humans suffering from the condition.



The future is sure to yield many promising developments, and perhaps one day Parkinson's will be a condition of the past. However, in the interim, it is crucial to keep faith in the current treatments and medications in a bid to halt the developments of the condition and promote extended healthy and happy lives for the patients this disease affects. Research is continually ongoing into a diverse range of related issues, and this will hopefully pay dividends in knowledge on the condition in the years to follow.

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